Basic Information
VIS ID
TVIS30006865
Fusion event
HIV-BRD7 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
50352357/50318446 (Hg38)
End
50352357/50318446 (Hg38)
Orient
-
Location type
Intronic
Target gene
BRD7
miRNAs that regulate target gene
hsa-mir-200c-3p ; hsa-mir-1296-5p ; hsa-mir-877-3p ; hsa-mir-99a-5p ; hsa-mir-218-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-503-3p ; hsa-mir-6861-5p ; hsa-mir-4301 ; hsa-mir-382-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-4761-3p ; hsa-mir-624-3p
Nearest miRNA
hsa-mir-1225/Upstream/25771; hsa-mir-11401/Downstream/423859;
Nearest TSS
ENST00000527434/Upstream/5342; ENST00000568427/Downstream/1483;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/71752, chr16-CpG: 98/Downstream/49882
Nearby gene
ADCY7(No orient, 312)
Nearest cancer related gene
BRD7(TSG, No orient, 0)
Upstream sequence
TTTATAGAAGGATTGTATAAGGGCCTTCAAACTTAATTTGTTCACTGAACAAGGCTATCTATCTATCTATCTCCATCCTGATTTTTTTCCCTTGTGTATA
Downstream sequence
ACAGGTTCTATACCGATTCAGCAAAATCACCATTTATCTCAGCTTGCTGATAAAAGGGGGCCATGAATCTTGTGGTCTCCTACTTAGAGTTCAACTCCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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