Basic Information
VIS ID
TVIS30006894
Fusion event
HIV-DUS2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
68093186/68059283 (Hg38)
End
68093186/68059283 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
DUS2
miRNAs that regulate target gene
hsa-mir-324-3p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-1262 ; hsa-mir-137 ; hsa-mir-25-3p ; hsa-mir-3194-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4278 ; hsa-mir-4701-3p ; hsa-mir-4710 ; hsa-mir-4711-3p ; hsa-mir-4716-3p ; hsa-mir-511-5p ; hsa-mir-6732-5p ; hsa-mir-6736-5p ; hsa-mir-6747-5p ; hsa-mir-6748-5p ; hsa-mir-6752-5p ; hsa-mir-6755-5p ; hsa-mir-6794-5p ; hsa-mir-6804-5p ; hsa-mir-6805-5p ; hsa-mir-6830-3p ; hsa-mir-6842-5p ; hsa-mir-6858-3p ; hsa-mir-7110-5p
Nearest miRNA
hsa-mir-1225/Upstream/856888; hsa-mir-11401/Downstream/174143;
Nearest TSS
ENST00000527434/Upstream/21279; ENST00000565980/Downstream/18669;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/35833, chr16-CpG: 134/Downstream/25378
Upstream sequence
ccctgggccacagagtgagaccctatatgagaaacaaaagaaaaaaaaaaGTATAGATTGAAACATTTCCCATTCCTTAGGCAGGGAGACTTCTTACTCG
Downstream sequence
TTACCCATTTGAATCTCTCAAATTTTGAATGTTTTACCTATTCAAAAAAGCAAGTAAGTTTAATAGAAACGAAGGAAGGAAGGAAATTCCATTGTTGAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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