Basic Information
VIS ID
TVIS30006988
Fusion event
HIV-POLR2A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
7393905/7490586 (Hg38)
End
7393905/7490586 (Hg38)
Orient
-
Location type
Intronic
Target gene
POLR2A
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-744-5p ; hsa-mir-454-3p ; hsa-mir-652-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-93-5p ; hsa-mir-17-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1253/Upstream/267207; hsa-mir-10226/Downstream/597470;
Nearest TSS
ENST00000595228/Upstream/5966; ENST00000576952/Downstream/7195;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/5579, chr17-CpG: 50/Downstream/58247
Upstream sequence
tgtccagcctagtgaaaccccgtctgtactaaaaatataaaaagcagctgggtgtagtcgtgggtgcctgtaatcccagctacttgggaggctgaggcat
Downstream sequence
atgaaccacttgaacctggtaggcggaggttgtactgacccaagatGGAATAATAACAAATAAAAGTATGGGACACTGTTGACAAAGCTCTACCAGAGTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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