Basic Information
VIS ID
TVIS30006999
Fusion event
HIV-MYH10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8507806/8604488 (Hg38)
End
8507806/8604488 (Hg38)
Orient
-
Location type
Intronic
Target gene
MYH10
miRNAs that regulate target gene
hsa-mir-1274a ; hsa-mir-106b-3p ; hsa-mir-92b-3p ; hsa-mir-505-3p ; hsa-mir-197-3p ; hsa-mir-26a-5p ; hsa-mir-23a-3p ; hsa-mir-200a-3p
Nearest miRNA
hsa-mir-1253/Upstream/417484; hsa-mir-10226/Downstream/3477411;
Nearest TSS
ENST00000595228/Upstream/50199; ENST00000585297/Downstream/405;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/127267, chr17-CpG: 188/Downstream/25198
Upstream sequence
AACACATGCTTTTTAACTTTTATTGTCACCCTTTTACATGCATTTAAATCACAAATAATACTTTACAATTTTTCTTTCCCCAGTGCAGCATCTACCTTTC
Downstream sequence
CTATTATTCTTCCTATTGGTTTTAAAACCTAATATAATGAGCTTTGGTTAGACCGCCTTGTGGTGGGAATCAAATGTATATGAAAACTAGATGCTTTTTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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