Basic Information
VIS ID
TVIS30007117
Fusion event
HIV-HEXIM1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43229263/45151896 (Hg38)
End
43229263/45151896 (Hg38)
Orient
+
Location type
UTR3
Target gene
HEXIM1
miRNAs that regulate target gene
hsa-mir-503-5p ; hsa-mir-324-3p ; hsa-mir-222-3p ; hsa-mir-20a-5p ; hsa-mir-17-3p ; hsa-mir-17-5p ; hsa-mir-5093 ; hsa-mir-223-3p ; hsa-mir-4697-3p ; hsa-mir-8065 ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-203a-3p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-1252-3p ; hsa-mir-548av-3p
Nearest miRNA
hsa-mir-1180/Upstream/37463; hsa-mir-10226/Downstream/323467;
Nearest TSS
ENST00000595228/Upstream/3394; ENST00000591070/Downstream/7559;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/1647, chr17-CpG: 83/Downstream/8997
Upstream sequence
ctccttgaaggttcagaacctctgCAGGGAAGGGGGAAGAAAACCCTCCCATTAGGAAGCATGCTTTTGCAGTTAAATGGCGATGGTGGAGGTGATAGGG
Downstream sequence
ACTTCAAGAGTAAAATGCACCTTGTATTGCATAAGAAGCATACACAAATCAATAAATCAAGGGAGATTATACCAGTAGGACTGAATCAGGGCCTTCAAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate