Basic Information
VIS ID
TVIS30007121
Fusion event
HIV-MAP3K14 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43388443/45311077 (Hg38)
End
43388443/45311077 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAP3K14
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-520e ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1180/Upstream/196644; hsa-mir-10226/Downstream/164286;
Nearest TSS
ENST00000595228/Upstream/20101; ENST00000592389/Downstream/5940;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/48612, chr17-CpG: 108/Downstream/5448
Upstream sequence
GTTGTGGTAGGGGAATAAAAGGAGAAGCTAGTTTAAAAAAAAAAATCCTGCTTCAGGATTAGTTCCTTCGTTCCCTggcagcagagtacagtgaagagtc
Downstream sequence
tgggttttatagttcaggctctgccattaactagctgtgtggccttgggcaacccacttggctttcttgggccaccattttctcttctgcaTTTTCTCAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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