Basic Information
VIS ID
TVIS30007176
Fusion event
HIV-TLK2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
60575635/62498274 (Hg38)
End
60575635/62498274 (Hg38)
Orient
+
Location type
Intronic
Target gene
TLK2
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6078 ; hsa-mir-3156-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-1538 ; hsa-mir-4745-3p ; hsa-mir-4733-3p ; hsa-mir-6504-3p ; hsa-mir-1911-3p ; hsa-mir-4747-3p ; hsa-mir-4438 ; hsa-mir-6776-3p ; hsa-mir-7641 ; hsa-mir-4695-3p ; hsa-mir-6790-3p ; hsa-mir-4494 ; hsa-mir-4499
Nearest miRNA
hsa-mir-10226/Upstream/2455169; hsa-mir-1250/Downstream/445941;
Nearest TSS
ENST00000595228/Upstream/17153; ENST00000581286/Downstream/54031;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/18467, chr17-CpG: 122/Downstream/128907
Upstream sequence
GTACTATTGCAAGGAAAATTTCATTCACCGTAACAGATTCCTTAGGGCTTTCAGGTTTTGGGATATTGGAATTAATTTGTAATATACATATTATCAAAAG
Downstream sequence
TTATAATTCCTAGTTTTTAGGTCTTGGAGAGAAAACAGTAGCACCATGTAATGAATTAGAAAGTTAAAAGATTTAGTTAACTTAAACATAGTTGATAGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate