Basic Information
VIS ID
TVIS30007181
Fusion event
HIV-MAP3K3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
61708363/63631003 (Hg38)
End
61708363/63631003 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAP3K3
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-9-5p ; hsa-mir-132-3p ; hsa-mir-124-3p ; hsa-mir-193b-3p ; hsa-mir-181a-5p ; hsa-mir-188-5p ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-1178-5p ; hsa-mir-1182 ; hsa-mir-4328 ; hsa-mir-3613-3p ; hsa-mir-6753-3p ; hsa-mir-6885-3p ; hsa-mir-7107-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-181d-5p ; hsa-mir-519d-3p ; hsa-mir-2052 ; hsa-mir-3140-3p ; hsa-mir-140-3p ; hsa-mir-182-5p ; hsa-mir-183-5p ; hsa-mir-193a-3p ; hsa-mir-328-5p ; hsa-mir-4459 ; hsa-mir-4754 ; hsa-mir-4779 ; hsa-mir-6774-5p ; hsa-mir-6804-5p ; hsa-mir-759 ; hsa-mir-3119 ; hsa-mir-892b
Nearest miRNA
hsa-mir-10226/Upstream/686691; hsa-mir-1250/Downstream/869771;
Nearest TSS
ENST00000595228/Upstream/8293; ENST00000585302/Downstream/35983;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7635, chr17-CpG: 221/Downstream/68527
Upstream sequence
CTTTATAGGCAACTTTGTCCTTTTCTGTACCTCGTCAGAGGGCATATAGGGCACCAGAGCAGATTTCGTCTAGGAAGAGGGGAGAGGCAAATAAGGTGAG
Downstream sequence
Gggccaggcacggtggcttatgtctgtaatcccagcattttgggaggctaaggagggaggatcgcttgagctcaggtgtttgaaatcagcctgggcaaca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate