Basic Information
VIS ID
TVIS30007327
Fusion event
HIV-ACAA2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
47310558/49784188 (Hg38)
End
47310558/49784188 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACAA2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-186-5p ; hsa-mir-6776-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6844 ; hsa-mir-7977 ; hsa-mir-143-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6499-3p ; hsa-mir-9-5p ; hsa-mir-5693 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-2/Upstream/296766; hsa-mir-122/Downstream/342311;
Nearest TSS
ENST00000575820/Upstream/42125; ENST00000615535/Downstream/2431;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/222030, chr18-CpG: 60/Downstream/28853
Upstream sequence
GACTTTGGAAAGCTGAAAGTTTTTAATCAAAAAAAACAAAAAACAAAGAACAAAAACAAACACCAGAAGAGGGAGGCAAACTAAAAAGGAGATGAGTGGA
Downstream sequence
TTTAGGGTTATAGAGTAGATTTAGGGTATATGAAACACATACAGAAGCTTGTGTGTGTTACGGGAAAGGAGTGAGAAGAGGAGGTAACTGGATAAATGGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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