Basic Information
VIS ID
TVIS30007332
Fusion event
HIV-WDR7 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
54425103/56757872 (Hg38)
End
54425103/56757872 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18B
Target gene
WDR7
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-18a-3p
Nearest miRNA
hsa-mir-1-2/Upstream/1278574; hsa-mir-122/Downstream/1693202;
Nearest TSS
ENST00000575820/Upstream/547; ENST00000586124/Downstream/116098;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/106318, chr18-CpG: 24/Downstream/363856
Upstream sequence
accagcctgagcagcatagaccctgcctctgcaaaaataaaagtaattagctgggcatggtggttacatgcatgtagtcccagctacttggggggctgag
Downstream sequence
gtgggagggtcgcttgagcctggaagttcgtggctgcagtgagccacgattgtgccactgtactccagcctaagcaacagagtaagactctgtctcaaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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