Basic Information
VIS ID
TVIS30007355
Fusion event
HIV-MIER2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
342268/342268 (Hg38)
End
342268/342268 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
MIER2
miRNAs that regulate target gene
hsa-mir-423-5p ; hsa-mir-106b-5p ; hsa-let-7b-5p ; hsa-mir-3660 ; hsa-mir-4499 ; hsa-mir-4513 ; hsa-mir-4526 ; hsa-mir-6087 ; hsa-mir-6855-3p ; hsa-mir-7-5p ; hsa-mir-873-5p ; hsa-mir-888-3p
Nearest miRNA
hsa-mir-1302-11/Upstream/270158; hsa-let-7e/Downstream/462672;
Nearest TSS
ENST00000633603/Upstream/1669; ENST00000591757/Downstream/2510;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/30044, chr19-CpG: 70/Downstream/1896
Upstream sequence
Cactcctccgtctgaccaatgttccctgggcgcccactctgggctcagcaaggcagtggcgtggtggttaacctgagaaacaagttccacctgcctccac
Downstream sequence
ccacatggagttgctagttttggacacagacaacaaacaagtggacatgtaTGGTACCGAGAAGAGAAAACAGGGCGCACGGGCTCTGCAACTGCGGGTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate