Basic Information
VIS ID
TVIS30007356
Fusion event
HIV-CDC34 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
538106/538106 (Hg38)
End
538106/538106 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
CDC34
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-3160-3p ; hsa-mir-3661 ; hsa-mir-4254 ; hsa-mir-4633-3p ; hsa-mir-492 ; hsa-mir-619-3p ; hsa-mir-631 ; hsa-mir-6500-5p ; hsa-mir-665 ; hsa-mir-6874-5p
Nearest miRNA
hsa-mir-1302-11/Upstream/465996; hsa-let-7e/Downstream/266834;
Nearest TSS
ENST00000633603/Upstream/1153; ENST00000593036/Downstream/3111;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1323, chr19-CpG: 136/Downstream/1915
Upstream sequence
GTCTGTGCTTTAATGAAGAAATGGGGTCGTGCTGTGTGTGCCCAGTGACTGACTGTTAGGGAACATGTGTCTGTGCCTTAATGAAGAAATGGGGTCGTGC
Downstream sequence
TGTGTGTGCCCAGTGACTGACTGTTAGGGAACATGTGTCTGTGCTTTAATGAAAAAATGGGGTCGTGCTGTGTGTGCCCAGTGACTGACTGTTAGTCAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate