Basic Information
VIS ID
TVIS30007371
Fusion event
HIV-THOP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2792783/2792785 (Hg38)
End
2792783/2792785 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
THOP1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-24-3p ; hsa-mir-19b-3p ; hsa-mir-935 ; hsa-mir-425-5p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-484 ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-1227/Upstream/161992; hsa-let-7e/Downstream/1168629;
Nearest TSS
ENST00000633603/Upstream/7218; ENST00000592639/Downstream/3222;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2066, chr19-CpG: 36/Downstream/6710
Upstream sequence
gctctgtcacccaggttggagtgcatggtgctgtcatggctcactgcagcctcaacctcccaggctcaagcgatcctcctgcctcagccttctaagtagc
Downstream sequence
tgagagcacaagtgtgtgccaccgtgcctggctaatttgtttttttAaactgctccattgagatatgatttgcataacatacagttcacccatttaaacc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate