Basic Information
VIS ID
TVIS30007427
Fusion event
HIV-ZNF136 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12290883/12180068 (Hg38)
End
12290883/12180068 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
ZNF136
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-8067 ; hsa-mir-4684-5p ; hsa-mir-6508-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-5680 ; hsa-mir-28-3p ; hsa-mir-6771-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-2278 ; hsa-mir-5692a ; hsa-mir-1276
Nearest miRNA
hsa-mir-1181/Upstream/684446; hsa-let-7e/Downstream/523533;
Nearest TSS
ENST00000633603/Upstream/16952; ENST00000476676/Downstream/4550;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16592, chr19-CpG: 66/Downstream/14669
Upstream sequence
cattctcctgcctcagcctcccgagtagctgggactacaggtgcccgccaccacacccggctaatttttttgtaattttagtagagacggggtttcacca
Downstream sequence
tgttagccaggatggtcttgatctcctgacctcgtgatctgcctgcctcggtctcccaaagtgctgggattacaggcgtgagccaccgcccccggccAAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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