Basic Information
VIS ID
TVIS30007463
Fusion event
HIV-ZNF486 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
20298187/20187378 (Hg38)
End
20298187/20187378 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF486
miRNAs that regulate target gene
hsa-let-7c-3p ; hsa-mir-1178-3p ; hsa-mir-377-3p ; hsa-mir-342-3p ; hsa-mir-216a-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-139-3p ; hsa-mir-4524a-3p ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4470 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-8073 ; hsa-mir-3128 ; hsa-mir-6849-3p ; hsa-mir-221-5p ; hsa-mir-183-5p ; hsa-mir-5583-3p ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-498 ; hsa-mir-3191-5p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-1306-5p ; hsa-mir-5571-5p
Nearest miRNA
hsa-mir-10395/Upstream/752220; hsa-let-7e/Downstream/211894;
Nearest TSS
ENST00000633603/Upstream/20104; ENST00000598131/Downstream/33041;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/135080, chr19-CpG: 19/Downstream/894980
Upstream sequence
ggttttaatgtactatttattgatttttaaatacaagattatacgatctacaaacagcgactttttacttatttttctttaatttcaatggattttttta
Downstream sequence
tttctttgactaattcttctgccacatgcttccagtgctacattaaaatagaagcattgacaatgggcaCAAtatagttttgtattggtgcctaaatttg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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