Basic Information
VIS ID
TVIS30007507
Fusion event
HIV-LTBP4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41126668/40620763 (Hg38)
End
41126668/40620763 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LTBP4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-218-5p ; hsa-mir-1304-5p ; hsa-mir-15a-3p ; hsa-mir-1827 ; hsa-mir-1972 ; hsa-mir-198 ; hsa-mir-219b-5p ; hsa-mir-3621 ; hsa-mir-3656 ; hsa-mir-3937 ; hsa-mir-4533 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4706 ; hsa-mir-4749-5p ; hsa-mir-4781-5p ; hsa-mir-505-3p ; hsa-mir-505-5p ; hsa-mir-523-3p ; hsa-mir-6125 ; hsa-mir-6765-5p ; hsa-mir-6777-5p ; hsa-mir-6825-5p ; hsa-mir-6889-5p
Nearest miRNA
hsa-mir-10395/Upstream/250856; hsa-let-7e/Downstream/1248864;
Nearest TSS
ENST00000633603/Upstream/3853; ENST00000598178/Downstream/1625;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6275, chr19-CpG: 25/Downstream/3179
Upstream sequence
tattcgaaaggctgaggcaggaaaatcgcttgaatccaggaggcggaggttgtgggattgcaccactgcactccagcctgggtgagagaggaagactccg
Downstream sequence
tcccaaaaaaaaaaaaaaaaaaaaaGCTATGTATTTAtttatttttaataatttccatctttactttagattcaggggatacatgtgcaggctttttacc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate