Basic Information
VIS ID
TVIS30007529
Fusion event
HIV-ZNF45 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
44426268/43922116 (Hg38)
End
44426268/43922116 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF45
miRNAs that regulate target gene
hsa-mir-29c-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-27b-3p ; hsa-mir-4291 ; hsa-mir-4329 ; hsa-mir-6761-5p ; hsa-mir-4251 ; hsa-mir-383-3p ; hsa-mir-3065-3p ; hsa-mir-205-3p ; hsa-mir-3200-5p ; hsa-mir-6871-3p
Nearest miRNA
hsa-mir-10395/Upstream/1570911; hsa-let-7e/Downstream/731570;
Nearest TSS
ENST00000633603/Upstream/2377; ENST00000591168/Downstream/171;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/20215, chr19-CpG: 35/Downstream/12932
Upstream sequence
CAACACAAAAGTAAAAAGCAGCAAGCATTTGGCACACAAGAGGTTCTCAAATGTCTACCGTTCTCCTTCATCTTCCTAACAAAGAGAATAAGGTGTATGT
Downstream sequence
AATCTTTCCGAAATGAGATGACAATTATTACGGAGAAAGGGAGGTCCAACTCACCTTAGACTTCGTCATTTTGTCCTCCTCCTTCTGGAGAAGTGCCAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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