Basic Information
VIS ID
TVIS30007545
Fusion event
HIV-BAX integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49460813/48957556 (Hg38)
End
49460813/48957556 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
BAX
miRNAs that regulate target gene
hsa-mir-504-5p ; hsa-mir-148b-3p ; hsa-mir-122-5p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-365a-3p ; hsa-mir-128-3p ; hsa-mir-214-3p ; hsa-mir-766-3p ; hsa-mir-298 ; hsa-mir-7-5p ; hsa-mir-34a-5p ; hsa-mir-181a-5p ; hsa-mir-15b-5p ; hsa-mir-148a-3p
Nearest miRNA
hsa-mir-10395/Upstream/1730535; hsa-let-7e/Downstream/52350;
Nearest TSS
ENST00000633603/Upstream/1703; ENST00000594305/Downstream/6419;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2320, chr19-CpG: 78/Downstream/7559
Nearest cancer related gene
BAX(OG, No orient, 0)
Upstream sequence
tagagacggagtttcgccatgttggccaggctggtctcaaactcctggcctcaagtgatccgcccaccttggcctcccaaagtgctgggattacaggcgt
Downstream sequence
gaaccactgcacccagcctggaaagactttaactttactctgagtgtgatgggagtgattggctggttttaaatacggaagcgacaagacctgatttata
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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