Basic Information
VIS ID
TVIS30007572
Fusion event
HIV-ZNF614 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.41
Reference genome
GRCh37/hg19
Start
52528338/52025085 (Hg38)
End
52528338/52025085 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF614
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-128-3p ; hsa-let-7c-5p ; hsa-mir-136-5p ; hsa-mir-5196-3p ; hsa-mir-3184-3p ; hsa-mir-125a-3p ; hsa-mir-31-3p ; hsa-mir-34a-3p ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-3529-3p ; hsa-mir-3934-5p ; hsa-mir-4436b-3p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-4632-5p ; hsa-mir-6735-5p ; hsa-mir-6879-5p ; hsa-mir-764 ; hsa-mir-7843-5p
Nearest miRNA
hsa-let-7e/Upstream/331746; hsa-mir-10394/Downstream/196935;
Nearest TSS
ENST00000633603/Upstream/16855; ENST00000614138/Downstream/3252;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16756, chr19-CpG: 42/Downstream/2985
Upstream sequence
ctcctgccaactacttgggaggctgaggcaagagaatggcgtgaacctgggaggcagagcttgcagtgagccaagactgcgccactgcactccagcctgg
Downstream sequence
gcaacagagcaagactctgtctcaaaataaataaataaataaatTAGTAATTTTAAAAAAGTTGGTTGGCAGGCACCAGCATGCAAAGAATGCCAATATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate