Basic Information
VIS ID
TVIS30007604
Fusion event
HIV-ITSN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
24566895/24344026 (Hg38)
End
24566895/24344026 (Hg38)
Orient
-
Location type
Intronic
Target gene
ITSN2
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-124-3p ; hsa-mir-21-5p ; hsa-mir-320c ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-3692-3p ; hsa-mir-513a-5p ; hsa-mir-16-1-3p ; hsa-mir-126-5p ; hsa-mir-551b-5p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-27b-3p ; hsa-mir-144-3p
Nearest miRNA
hsa-mir-3125/Upstream/4995521; hsa-mir-10b/Downstream/984614;
Nearest TSS
ENST00000437798/Upstream/15908; ENST00000469850/Downstream/16283;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/168226, chr2-CpG: 120/Downstream/15725
Upstream sequence
CTCCACAGACAGGGGAGGAGGGGTGAACCTGAAGACCCAGTCCTgattaccacagttaacagtttggtatttgtttttccagatttattttatgcatata
Downstream sequence
taaacaaacatgttatttttcaaacccaaataaaattatgctagccaattaatattctattattttcattacacatattacagatatccttccatagcaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate