Basic Information
VIS ID
TVIS30007650
Fusion event
HIV-PPM1B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
44443864/44216725 (Hg38)
End
44443864/44216725 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
PPM1B
miRNAs that regulate target gene
hsa-mir-106b-5p ; hsa-mir-8485 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-551b-5p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-1301/Upstream/8745239; hsa-mir-10b/Downstream/3160950;
Nearest TSS
ENST00000437798/Upstream/14708; ENST00000488866/Downstream/1097;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/47235, chr2-CpG: 30/Downstream/145090
Upstream sequence
ggatgaaaataggcattcatagctgggcgtggtggctcaggcctctaatcccagcattttgagaggctgaggtgggtggatcacgaggtcaggaattcaa
Downstream sequence
gaccagcctggccaacatggtgaaaccccatctctactaaaatacaaaaattagctgggtgtggtggcacatgcctgtaatcccagctacttgggaggct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate