Basic Information
VIS ID
TVIS30007665
Fusion event
HIV-EML6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
55076680/54849543 (Hg38)
End
55076680/54849543 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
EML6
miRNAs that regulate target gene
hsa-mir-302c-5p ; hsa-mir-215-5p ; hsa-mir-3143 ; hsa-mir-192-5p ; hsa-mir-6759-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-543 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p
Nearest miRNA
hsa-mir-1301/Upstream/1000338; hsa-mir-10b/Downstream/1133424;
Nearest TSS
ENST00000437798/Upstream/101139; ENST00000493997/Downstream/4308;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/124192, chr2-CpG: 129/Downstream/199876
Upstream sequence
TACTTTGGAAGCCCAAAATATCATTTAAACAGTTTGTTATTCTCCTAAAATGCCATAAAttttaagacggagtcttgctctgtcgcccaagctggagtgc
Downstream sequence
agtggtgccatcttgactcactgcaaactctacctcccaggttcacgccattctcctgcctcagcctcccgattagctgggactacaggcgcctgccacc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate