Basic Information
VIS ID
TVIS30007707
Fusion event
HIV-MRPL19 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
75884478/75657352 (Hg38)
End
75884478/75657352 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA2S
Target gene
MRPL19
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-590-3p ; hsa-mir-1-3p ; hsa-mir-19b-3p ; hsa-mir-1252-3p ; hsa-mir-4722-3p ; hsa-mir-6727-3p ; hsa-mir-7152-5p ; hsa-mir-8061 ; hsa-mir-3074-5p ; hsa-mir-4760-5p ; hsa-mir-4775 ; hsa-mir-6817-5p ; hsa-mir-4524a-3p ; hsa-mir-4769-3p ; hsa-mir-6747-3p ; hsa-mir-5580-3p ; hsa-mir-3662 ; hsa-mir-1910-5p ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4436b-5p ; hsa-mir-4764-3p ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/566438; hsa-mir-10b/Downstream/3991942;
Nearest TSS
ENST00000437798/Upstream/2452; ENST00000604845/Downstream/3110;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/10058, chr2-CpG: 64/Downstream/53179
Upstream sequence
aaggggctgtcTTTAGGATTATCTGAATGGGCTTTTTTGGGAGTCCCCTCCTCCACATGAATAttttggttttgtcagattccctagaatagaggcttcc
Downstream sequence
aatctccttcctggagggGTCTGTCCAGGAAGGAGATTGTCTAGGGGTCTGTCAGACAGCAGCTTTCAGCTACTTCCTTGATCTTTTTCACTAATGATTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate