Basic Information
VIS ID
TVIS30007736
Fusion event
HIV-EIF5B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
100004452/99387989 (Hg38)
End
100004452/99387989 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
EIF5B
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/2589636; hsa-mir-10b/Downstream/1921461;
Nearest TSS
ENST00000437798/Upstream/47287; ENST00000470868/Downstream/1618;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/50052, chr2-CpG: 202/Downstream/101092
Upstream sequence
ctcgaacacctgggctgaagcaatctgcccacgtcagcctcccaaagtgctaagatttaagacctgagccaccatgcctggccaggccttctttactttc
Downstream sequence
tcttggcaatattttgtagttttattgtccacatgttggacatatttttctgaatttatccctaagtatttcatggtttaatgctattgtaaatagcatg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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