Basic Information
VIS ID
TVIS30007756
Fusion event
HIV-ANAPC1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
112565684/111808107 (Hg38)
End
112565684/111808107 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
ANAPC1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-100-5p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4668-3p ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-1226-5p ; hsa-mir-4279 ; hsa-mir-6868-3p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-1266-3p ; hsa-mir-548c-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/36973; hsa-mir-10b/Downstream/1774852;
Nearest TSS
ENST00000437798/Upstream/13067; ENST00000473065/Downstream/13649;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/583349, chr2-CpG: 63/Downstream/75653
Nearest cancer related gene
ANAPC1(TSG, No orient, 0)
Upstream sequence
ACTAAATTATGGGTCCCAATCTTCACTGGTTCTCTCTTAGGTTTCTATCAACACCACGAGAGAAACACACCCTCCAGCCTGGGTCCCAGAATGAGGCAGG
Downstream sequence
TGAGGCAGAACGGCAGCAGAACAGCCGGCTACACATCTACAGCCTAAAGCAGAGCTGCCTGGGCCAATGCTATGCCTGTATGTATGTAGCATCACTGTGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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