Basic Information
VIS ID
TVIS30007757
Fusion event
HIV-ZC3H8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
112987027/112229450 (Hg38)
End
112987027/112229450 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
ZC3H8
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-218-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-34b-3p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-7160-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/458316; hsa-mir-10b/Downstream/1353509;
Nearest TSS
ENST00000437798/Upstream/47567; ENST00000476511/Downstream/2435;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/42005, chr2-CpG: 67/Downstream/25081
Upstream sequence
AGTTATACTCTTTTTTCATTCATTCTACcagttcctcccacatgtaaagtacaaaaggtggagtacagtttccttctccttgactttgggcttggccata
Downstream sequence
tgacttactttagccaatgggttataagtaaatgtgctgtaaacagggctttgccctcttgagtttctgccaacaccatgagaagaacatgccctagcta
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate