Basic Information
VIS ID
TVIS30007801
Fusion event
HIV-ACVR1C integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
158416475/157559963 (Hg38)
End
158416475/157559963 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACVR1C
miRNAs that regulate target gene
hsa-mir-376c-3p ; hsa-mir-376a-3p ; hsa-mir-376a-5p ; hsa-mir-376b-3p ; hsa-mir-22-3p ; hsa-mir-412-3p ; hsa-mir-147a ; hsa-mir-122-5p ; hsa-mir-6794-3p ; hsa-mir-3682-5p ; hsa-mir-6837-3p ; hsa-mir-676-5p ; hsa-mir-4639-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-4699-3p ; hsa-mir-323a-3p
Nearest miRNA
hsa-mir-128-1/Upstream/6191552; hsa-mir-10b/Downstream/1626872;
Nearest TSS
ENST00000437798/Upstream/71002; ENST00000604340/Downstream/37597;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1123466, chr2-CpG: 31/Downstream/37324
Nearest cancer related gene
ACVR1C(TSG, No orient, 0)
Upstream sequence
agaaaagggggaagggagagaaggagagagggaaggaaggaaagaggaaggaagaaggaaggaaaaaggaaagagagagagaagcaaggaggcagggagg
Downstream sequence
gaaggaagaaaaggagggagggagggaggaaacgaaggaaggaaggaaggaaATTTTAATTTATCTTTGTGAGTTTTGCAACTCTCCCTGGAGACCTGCG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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