Basic Information
VIS ID
TVIS30007818
Fusion event
HIV-DYNC1I2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
172580835/171724325 (Hg38)
End
172580835/171724325 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
DYNC1I2
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-3924 ; hsa-mir-4789-5p ; hsa-mir-496 ; hsa-mir-5583-5p ; hsa-mir-3129-3p
Nearest miRNA
hsa-mir-128-1/Upstream/3141307; hsa-mir-10b/Downstream/3443308;
Nearest TSS
ENST00000437798/Upstream/8935; ENST00000479806/Downstream/2233;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/36145, chr2-CpG: 56/Downstream/197898
Upstream sequence
ACAGGTACAGTTATATTTTTATTGCCTATACTATAGAGTTAGAAAGATTTTCATAGCTCTCTAAACCTAACAGTATGTGTGTGGTTTGGCAGCTGGTGTG
Downstream sequence
GCCTACAAGCTGCATTTTGTTTGCTGGGTAAAGGCTTGTCTTTAGGCCTCCTGGAGTGCTGGTAATTGCACAGGCCTGCCATTGGGGAGAGACACAGGAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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