Basic Information
VIS ID
TVIS30007819
Fusion event
HIV-HAT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
172781816/171925306 (Hg38)
End
172781816/171925306 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
HAT1
miRNAs that regulate target gene
hsa-mir-32-5p ; hsa-mir-10b-3p ; hsa-mir-488-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-mir-4635 ; hsa-let-7a-3p ; hsa-mir-3613-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-548c-3p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-493-5p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-let-7c-3p ; hsa-mir-513a-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-1261 ; hsa-mir-4536-5p ; hsa-mir-4494 ; hsa-mir-4463 ; hsa-mir-1243 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-542-3p ; hsa-mir-3941 ; hsa-mir-5190 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-486-5p
Nearest miRNA
hsa-mir-128-1/Upstream/3342288; hsa-mir-10b/Downstream/3242327;
Nearest TSS
ENST00000437798/Upstream/2699; ENST00000392584/Downstream/39527;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2517, chr2-CpG: 59/Downstream/74400
Upstream sequence
ggattacaggcgcccgtcaccgtgcccggctaatttttgtatttttagtagagacgggtttcaccatcttggcgaggctgacctcgaactcctgaccttg
Downstream sequence
tgatccacccacctcagcctcccagagtgctgggattacaggcgtgagccaccgtgcccagcTGGCATTCTTAATACATTTATTTAAGAGTATGTGGAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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