Basic Information
VIS ID
TVIS30007828
Fusion event
HIV-WIPF1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
175426889/174562161 (Hg38)
End
175426889/174562161 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA2G
Target gene
WIPF1
miRNAs that regulate target gene
hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-124-3p ; hsa-mir-200c-3p ; hsa-mir-1288-3p ; hsa-mir-5002-3p ; hsa-mir-3917 ; hsa-mir-99b-3p ; hsa-mir-99a-3p
Nearest miRNA
hsa-mir-128-1/Upstream/5979143; hsa-mir-10b/Downstream/605472;
Nearest TSS
ENST00000437798/Upstream/14787; ENST00000454203/Downstream/8485;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/74735, chr2-CpG: 122/Downstream/119973
Upstream sequence
AGATTGGACATCCTGTGACTGCAAGTTTCCAGTGAGCCCTTACTCAGCAGCTTGCTTAGGTGGTCTGTGGTTCATAGAAACAGAGAGGAGGCCAAGCATG
Downstream sequence
CGAAAAAGGAACGGGAGAAAACAGCTCTCAGGGACTTTAATAATTACAGTCTGTAACAAATAAGCAGTGAATGTTTGAATTTGGTTGGTGGAAAGCTGGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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