Basic Information
VIS ID
TVIS30007853
Fusion event
HIV-ITGAV integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
187497086/186632359 (Hg38)
End
187497086/186632359 (Hg38)
Orient
-
Location type
Intronic
Target gene
ITGAV
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-215-5p ; hsa-mir-196a-5p ; hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-mir-218-5p ; hsa-mir-548c-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-10b/Upstream/2253315; hsa-mir-1244-1/Downstream/1665133;
Nearest TSS
ENST00000437798/Upstream/32154; ENST00000460641/Downstream/32767;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/41737, chr2-CpG: 39/Downstream/61530
Nearest cancer related gene
ITGAV(TSG, No orient, 0)
Upstream sequence
tttaaaatatataatGTCCATCTTTTCTGTATTGATGCCTATACAACCATAACCCCAGAAGTACTCTCATACTGTGAAAGTCATTGCTAAATTAGGTATT
Downstream sequence
CACTTTCTTAAACACATTTCTGAGAAAAGGGTGTCTTTTTAGGGCAGATGACTTAGAAGTTCTTTTACGTAGCCAAGGCAAAAGATTGTCTATTGAAAGC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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