Basic Information
VIS ID
TVIS30007855
Fusion event
HIV-WDR75 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
190320290/189455564 (Hg38)
End
190320290/189455564 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR75
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-3119 ; hsa-mir-552-5p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-627-3p ; hsa-mir-6506-3p ; hsa-mir-4762-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-1228-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-7977 ; hsa-mir-30c-1-3p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4726-3p ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-10b/Upstream/322453; hsa-mir-1244-1/Downstream/17327670;
Nearest TSS
ENST00000437798/Upstream/14071; ENST00000498365/Downstream/6920;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/13857, chr2-CpG: 68/Downstream/125169
Upstream sequence
TTTCTGTTTTGTACCTAAAATTTCTTTCCTGCAATCTCTCTTCTGAGCATTTTATGTTACAGTGATTTTATATTCCCTTGAATTACTATATTTGTATTAG
Downstream sequence
TAACTAAGAAGCCTCTTCATTGCTTTAGCATGTATTTATGGTATAGATTTTTTTAGGACTATCCTTATTTTTGTGTGTTCTGTCCTATTGCCTTTGTAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate