Basic Information
VIS ID
TVIS30007866
Fusion event
HIV-HECW2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
197098148/196233424 (Hg38)
End
197098148/196233424 (Hg38)
Orient
+
Location type
Intronic
Target gene
HECW2
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-944 ; hsa-mir-7977 ; hsa-mir-617 ; hsa-mir-499b-5p ; hsa-mir-6507-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-1254 ; hsa-mir-1910-3p ; hsa-mir-2114-3p ; hsa-mir-2467-3p ; hsa-mir-3116 ; hsa-mir-3202 ; hsa-mir-3714 ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-4533 ; hsa-mir-455-3p ; hsa-mir-5694 ; hsa-mir-605-3p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6807-5p ; hsa-mir-6823-3p
Nearest miRNA
hsa-mir-10b/Upstream/7100313; hsa-mir-1244-1/Downstream/10549810;
Nearest TSS
ENST00000437798/Upstream/15165; ENST00000430904/Downstream/9402;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/61765, chr2-CpG: 138/Downstream/359244
Upstream sequence
CATTTTAAATATCATCACATGGCTGGGTTGGCACTCCACCCAAGTTGTCAGTGGCACCCAAAATTTGTTAAAATAACAAATTTTATTCTCCCATTCTTTA
Downstream sequence
TTTTCAACTAAGAATTACTGAAAACTAAGTATTCTAATGAAAGCAGACTATAAAATGAAAGAAGATGATGGCCTTGGGAAGTCACACCATTTCCTACAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate