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VISDB
Viral Integration Site DataBase
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TVIS30007874
Basic Information
VIS ID
TVIS30007874
Fusion event
HIV-CASP8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
202140242/201275519 (Hg38)
End
202140242/201275519 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
CASP8
miRNAs that regulate target gene
hsa-let-7a-5p
;
hsa-mir-19b-1-5p
;
hsa-mir-26b-5p
;
hsa-mir-106b-5p
;
hsa-mir-5682
;
hsa-mir-767-5p
;
hsa-mir-6871-3p
;
hsa-mir-29c-3p
;
hsa-mir-29b-3p
;
hsa-mir-29a-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-665
;
hsa-mir-6771-5p
;
hsa-mir-6735-3p
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-6746-5p
;
hsa-mir-4768-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-376a-3p
;
hsa-mir-34a-5p
;
hsa-mir-296-5p
;
hsa-mir-21-5p
;
hsa-mir-2392
;
hsa-mir-362-5p
;
hsa-mir-3682-5p
;
hsa-mir-376b-3p
;
hsa-mir-4704-3p
;
hsa-mir-4710
;
hsa-mir-4793-5p
;
hsa-mir-5000-5p
;
hsa-mir-500b-5p
;
hsa-mir-5196-3p
;
hsa-mir-744-3p
;
hsa-mir-7855-5p
Nearest miRNA
hsa-mir-10b/Upstream/12142408; hsa-mir-1244-1/Downstream/5507715;
Nearest TSS
ENST00000437798/Upstream/2881;
ENST00000488196/Downstream/14203;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/156533
,
chr2-CpG: 110/Downstream/175611
Nearest cancer related gene
CASP8
(TSG, No orient, 0)
Upstream sequence
GCAGAAACATGTAATTTTTAGGCATAATAACTTCTCTTTATGTAATCAACAATCCACCAAATACATCCTGACTTATTAGACGATCTGCTCCTCCTCATGG
Downstream sequence
TAGGAAGAAGAGGAAATCCTGAATATCTGAAGTAGGCTTGAGAGAGATTATTCACTAGTGTGGGCTCCTGAGAAAATTACCAGACCTCTTTCATCTGAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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