Basic Information
VIS ID
TVIS30007975
Fusion event
HIV-EIF2S2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
32691009/34103203 (Hg38)
End
32691009/34103203 (Hg38)
Orient
-
Location type
Intronic
Target gene
EIF2S2
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-27a-3p ; hsa-mir-363-3p ; hsa-mir-7856-5p ; hsa-mir-4477b ; hsa-mir-6892-5p ; hsa-mir-8062 ; hsa-mir-1178-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-27b-3p ; hsa-mir-216a-3p ; hsa-mir-3681-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/54013; hsa-mir-1-1/Downstream/363122;
Nearest TSS
ENST00000382410/Upstream/25990; ENST00000568305/Downstream/9129;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/108419, chr20-CpG: 96/Downstream/8248
Upstream sequence
TTCAATATGTTACCAAAAGTTTAAGAAACCAAAGGAATATTTGCTCAGAAGGATTTCTCACTCATAGAAATAGTTCTCCACAGCCAAAAATCTCAGTATA
Downstream sequence
GTTAAGGACAAGGGACATTTGTGATCATCTTAATGGCACACAATACAATATGTAAGACCTAAATTTAAATTCCTTGAACCACAATCCCTTTAAGATACCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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