Basic Information
VIS ID
TVIS30008058
Fusion event
HIV-chr21 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
33973809/32601499 (Hg38)
End
33973809/32601499 (Hg38)
Orient
+
Location type
Intronic
Target gene
C21orf59-TCP10L ; CFAP298
miRNAs that regulate target gene
hsa-mir-10a-5p ; hsa-mir-4715-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-566 ; hsa-mir-6720-3p ; hsa-mir-4763-5p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6872-3p ; hsa-mir-4438 ; hsa-mir-6778-3p ; hsa-mir-4740-3p ; hsa-mir-139-5p ; hsa-mir-3684 ; hsa-mir-4794 ; hsa-mir-548v ; hsa-mir-582-5p ; hsa-mir-614 ; hsa-mir-664a-5p
Nearest miRNA
hsa-let-7c/Upstream/2226121; hsa-mir-3197/Downstream/949163;
Nearest TSS
ENST00000624081/Upstream/14126; ENST00000458479/Downstream/1738;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/31545, chr21-CpG: 93/Downstream/10558
Nearby gene
CFAP298(No orient, 175)
Upstream sequence
ccattctcctgcctcagcctcccgagtagctgggactacaggcgcctgccaccatgcccggctaattttttgtatttttagtagagacggggtttcaccg
Downstream sequence
tgttagcctggatggtcttgatctcctgacctcgtgatctgcctgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate