Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene333217513322990133297160332663583331018733229901332656753326471833271267332522683325763533228741332337923323633033240728332251893322831433249022332519513326387333266260332466953324880533243615332457053325928633260782332344633323560233261256332622013324165733242398332610183326101833273470
Basic Information
VIS ID
TVIS30008063
Fusion event
HIV-IL10RB integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
34645775/33273470 (Hg38)
End
34645775/33273470 (Hg38)
Orient
-
Location type
Intronic
Target gene
IL10RB
miRNAs that regulate target gene
hsa-mir-6749-3p ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-6890-3p ; hsa-mir-4284 ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6879-3p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-6514-5p
Nearest miRNA
hsa-let-7c/Upstream/2898092; hsa-mir-3197/Downstream/277192;
Nearest TSS
ENST00000624081/Upstream/5188; ENST00000451065/Downstream/3142;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/6700, chr21-CpG: 110/Downstream/50757
Upstream sequence
taagtgtgtgatagcgttatgtctaaaaaaatgtgcacagcttaattttaaaatatttacttgcggaaaaatggtagcaatcatcagagccttcagcaag
Downstream sequence
tcataatccttttgctcgtggagcatcttgccttgatatggatggctgctgactgatcagggtagtggttgctgagttgcagtgactgtgacaatttctt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate