Basic Information
VIS ID
TVIS30008082
Fusion event
HIV-ZBTB21 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
43419365/41999256 (Hg38)
End
43419365/41999256 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZBTB21
miRNAs that regulate target gene
hsa-mir-548b-3p ; hsa-mir-186-5p ; hsa-mir-140-3p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-425-5p ; hsa-mir-30e-5p ; hsa-mir-6507-5p ; hsa-mir-3119 ; hsa-mir-510-3p ; hsa-mir-488-3p ; hsa-mir-875-5p ; hsa-mir-4715-5p ; hsa-mir-4282 ; hsa-mir-6875-3p ; hsa-mir-2053 ; hsa-mir-569 ; hsa-mir-4772-5p ; hsa-mir-383-5p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-3919 ; hsa-mir-4756-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p
Nearest miRNA
hsa-let-7c/Upstream/252415; hsa-mir-5692b/Downstream/951672;
Nearest TSS
ENST00000624081/Upstream/45366; ENST00000412906/Downstream/8801;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/44976, chr21-CpG: 233/Downstream/9914
Upstream sequence
TTTGACAAAGCTAGTTCAGATGTTGCCACAGGGAAAAGCTGTAACACAGAATTAAAGGTACAGATTTAAAGGCTTGGATAGTCTTTGTCAAAaggggttc
Downstream sequence
ttaaactcaacttggtggtttaaaactagcaattaaaaaataaatgactaggacagagtagaaaatatcagaatgcatcaaatgtcataaggctaattat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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