Basic Information
VIS ID
TVIS30008093
Fusion event
HIV-ADARB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
46499681/45079766 (Hg38)
End
46499681/45079766 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADARB1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-148a-3p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-mir-193b-3p ; hsa-mir-17-5p ; hsa-mir-218-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-let-7c/Upstream/1469777; hsa-mir-6815/Downstream/398500;
Nearest TSS
ENST00000624081/Upstream/5166; ENST00000611195/Downstream/21328;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/4209, chr21-CpG: 53/Downstream/21114
Nearest cancer related gene
ADARB1(TSG, No orient, 0)
Upstream sequence
tcagggttgttgagttgctaatgtaaagtacctaaaatagtacctgactaacagtatttaatggggcttactttgcttattattTTTATGattagttatc
Downstream sequence
tgagtagagaaaggtgaatatggatggaaattcaaggtcaggttcaagaagaggttggggccaaatatgtaaatttgggagtcatttgcatattgctgat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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