Basic Information
VIS ID
TVIS30008094
Fusion event
HIV-ADARB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
46503747/45083832 (Hg38)
End
46503747/45083832 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADARB1
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-34a-5p ; hsa-mir-148a-3p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-mir-193b-3p ; hsa-mir-17-5p ; hsa-mir-218-5p ; hsa-mir-140-3p
Nearest miRNA
hsa-let-7c/Upstream/1473843; hsa-mir-6815/Downstream/394434;
Nearest TSS
ENST00000624081/Upstream/9232; ENST00000611195/Downstream/17262;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/8275, chr21-CpG: 53/Downstream/17048
Nearest cancer related gene
ADARB1(TSG, No orient, 0)
Upstream sequence
tgctcaggctagagtacagtggtacaatcatagctcactgtagccacaacctcctgggttcaagcgatcctcccgcctcagtctcagcctcccaggtagc
Downstream sequence
tggggctacaggtggatgccaccacacccggctaatttttgtattttttgtagagacggggttttaccgtgttgcccaggctggtctcgagctcctggac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate