Basic Information
VIS ID
TVIS30008112
Fusion event
HIV-KLHL22 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
20811975/20457688 (Hg38)
End
20811975/20457688 (Hg38)
Orient
-
Location type
Intronic
Target gene
KLHL22
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1286/Upstream/208477; hsa-let-7a-3/Downstream/576488;
Nearest TSS
ENST00000624155/Upstream/11068; ENST00000438962/Downstream/7798;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/19310, chr22-CpG: 109/Downstream/37384
Upstream sequence
GGGTCTGGATCCTTGATGAGCCTCCCCAGGTGGACTGGCTGAACCTCATGGGGCCTCATCAATGCATTCAATGCAGGGTCTCTGGAGAAGCATGGATTCT
Downstream sequence
GCTCACTGAGCCTGTTTCTCTGACCTGGGACAGGCCTTGACACCTAGGCCTCTCACTCTTTGCACATCCTGGGGAAGGAAATTAGGCAGGAGAAGGCCCC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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