Basic Information
VIS ID
TVIS30008135
Fusion event
HIV-HORMAD2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
30530581/30134592 (Hg38)
End
30530581/30134592 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22B
Target gene
HORMAD2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-580-3p ; hsa-mir-7153-5p ; hsa-mir-103a-2-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p
Nearest miRNA
hsa-mir-1286/Upstream/127479; hsa-let-7a-3/Downstream/596965;
Nearest TSS
ENST00000624155/Upstream/40634; ENST00000447565/Downstream/72517;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/54051, chr22-CpG: 19/Downstream/109148
Upstream sequence
TCTGCCAAATCCAGGAGAAAATGAGGCCAATTGTGTTTCTAACTTTTCTTTACCATTGTCAGAAGGACTGGTCTTCTGAAGTCTTAGCTCTCAATTTTGA
Downstream sequence
GATCCTAATATAAATGCTAAAAGAATTACTCCTCTTATGATGCTTAGATTTGTTACAAGCATAATCTCGTGTGTGTACCAACAGAGCCTTGCTCTGTCAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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