Basic Information
VIS ID
TVIS30008192
Fusion event
HIV-MRTFA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
40845633/40449629 (Hg38)
End
40845633/40449629 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
MRTFA
miRNAs that regulate target gene
hsa-mir-183-5p
Nearest miRNA
hsa-mir-1286/Upstream/2460776; hsa-let-7a-3/Downstream/364254;
Nearest TSS
ENST00000624155/Upstream/13319; ENST00000417123/Downstream/13789;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/30531, chr22-CpG: 107/Downstream/186496
Upstream sequence
AAGAATAATCTTTAGTAAGCTCTTTGGGTAATGCTAAAGCCACTAAATTCGGAAAACATTGCTTCCCTAATCTAACAAAGGCAAAGAAGAGGTGAGAAAG
Downstream sequence
TAAGAATTTTATTTGCTTATTCTCTAATACCAGGTGCTGATTAAAACTACACTTAGTAAAGAAGGACTTGCTGAATTTTCTCAATAGCTTGATTCAAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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