Basic Information
VIS ID
TVIS30008216
Fusion event
HIV-CERK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
47110163/46714266 (Hg38)
End
47110163/46714266 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
CERK
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-101-3p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-3614-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-16-1-3p ; hsa-mir-503-5p ; hsa-mir-144-3p ; hsa-mir-541-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-448 ; hsa-mir-153-3p ; hsa-mir-500a-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-767-5p ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-449b-3p ; hsa-mir-6753-5p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p
Nearest miRNA
hsa-let-7a-3/Upstream/600498; hsa-mir-12114/Downstream/1560098;
Nearest TSS
ENST00000624155/Upstream/20454; ENST00000496139/Downstream/23824;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/12562, chr22-CpG: 111/Downstream/23491
Upstream sequence
aggctgaggcaggagaatcacttgaacccaggaagtggaggttgcagtgagccaagatcgcgccattgcactccagcctgggtgacagagtaagactcca
Downstream sequence
tgtcaaaataaacaaacaaacaaacaaattagctgggtgtggtggtatgcccttgtagtcccagctactctggaggctgaggtgagagaatcacttgaac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate