Basic Information
VIS ID
TVIS30008261
Fusion event
HIV-METTL6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
15460398/15418891 (Hg38)
End
15460398/15418891 (Hg38)
Orient
+
Location type
Intronic
Target gene
METTL6
miRNAs that regulate target gene
hsa-let-7a-5p ; hsa-mir-7109-5p ; hsa-mir-6085 ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-6824-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6825-5p ; hsa-mir-3175 ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-4731-5p ; hsa-mir-3150b-3p ; hsa-mir-637 ; hsa-mir-6783-5p
Nearest miRNA
hsa-mir-12127/Upstream/5024329; hsa-let-7g/Downstream/77348;
Nearest TSS
ENST00000440867/Upstream/2984; ENST00000449565/Downstream/6144;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/86189, chr3-CpG: 46/Downstream/8534
Upstream sequence
aggctgagacaggaggatcgcttgaacccaagagttcgagagcagcctgggatagtgagacctgatctctaagaaaaataaaGTAAATCCTAGGAGTAAA
Downstream sequence
GGACTCCTAAACAAGACATAAAATAGAACTTCAAAAGGAAAAGATTAATATTTTGCCATGATAATTTAAATCCTGTGTagcctgggcaacacagcaggac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate