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Viral Integration Site DataBase
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TVIS30008310
Basic Information
VIS ID
TVIS30008310
Fusion event
HIV-ZNF589 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
48287812/48246322 (Hg38)
End
48287812/48246322 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF589
miRNAs that regulate target gene
hsa-mir-30b-5p
;
hsa-mir-1273e
;
hsa-mir-139-3p
;
hsa-mir-298
;
hsa-mir-1827
;
hsa-mir-219b-3p
;
hsa-mir-4649-3p
;
hsa-mir-6840-3p
;
hsa-mir-4768-3p
;
hsa-mir-665
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-302f
;
hsa-mir-4724-3p
;
hsa-mir-6849-3p
;
hsa-mir-4999-3p
;
hsa-mir-4461
;
hsa-mir-3680-5p
;
hsa-mir-7849-3p
;
hsa-mir-6750-3p
;
hsa-mir-6771-5p
;
hsa-mir-7977
;
hsa-mir-7160-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-6746-5p
;
hsa-mir-5690
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
Nearest miRNA
hsa-mir-12127/Upstream/49706; hsa-let-7g/Downstream/70038;
Nearest TSS
ENST00000440867/Upstream/5167;
ENST00000454212/Downstream/10265;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/4995
,
chr3-CpG: 67/Downstream/54772
Upstream sequence
cttgagcccaggaggtggaggttgtaatgagcagagattgtgccactgcattccagcctgggcaatagtgagaccctatctcaatcaatcaatcaatcaa
Downstream sequence
tcaGTTCCACAATAATTTGAAGAGGAATGAGAGTCTGACAAGCTGCGCTTTAGAAATGCTGTTGTAATGGTCTTTAATACTTTTTTCTCCTTTTACTCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Central Memory CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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