Basic Information
VIS ID
TVIS30008354
Fusion event
HIV-APPL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
57291799/57257771 (Hg38)
End
57291799/57257771 (Hg38)
Orient
-
Location type
Intronic
Target gene
APPL1
miRNAs that regulate target gene
hsa-mir-340-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-96-5p ; hsa-mir-32-5p ; hsa-mir-21-5p ; hsa-mir-877-3p ; hsa-mir-423-3p ; hsa-mir-324-3p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-3148 ; hsa-mir-526b-5p ; hsa-mir-335-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-1250-3p ; hsa-mir-2909 ; hsa-mir-7977 ; hsa-mir-1296-5p ; hsa-mir-6781-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p
Nearest miRNA
hsa-let-7g/Upstream/1405177; hsa-mir-12124/Downstream/3360034;
Nearest TSS
ENST00000440867/Upstream/4089; ENST00000492501/Downstream/992;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/29201, chr3-CpG: 113/Downstream/298433
Upstream sequence
TATTTCTTGGATACTTGCTCTTAAAATTGCAGAAGAAAGTTGATAGCTGTCTTTAGGTCATGACAATTTTTAAAAAATTCTTGAGGGTAATACATGTGAT
Downstream sequence
ATAGGTTTATTAGAAAATATTATCTTATACCAGAATAAGAAATCTTCAGGAAGTTACTAAAACATTATCACTATTATGAATTATGAATGAGTCATTGTTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate