Basic Information
VIS ID
TVIS30008359
Fusion event
HIV-FHIT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
60062342/60076616 (Hg38)
End
60062342/60076616 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
FHIT
miRNAs that regulate target gene
hsa-mir-143-3p ; hsa-mir-217 ; hsa-mir-331-3p ; hsa-mir-625-5p
Nearest miRNA
hsa-let-7g/Upstream/4224022; hsa-mir-12124/Downstream/541189;
Nearest TSS
ENST00000440867/Upstream/62466; ENST00000475527/Downstream/4224;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1026398, chr3-CpG: 48/Downstream/1174316
Nearest cancer related gene
FHIT(TSG, No orient, 0)
Upstream sequence
GATTCTTCTCTTATTCTCTACTTCTGCTTCTGCTGCTGCTGCTTTTTTTAAACAAATGAGATCAGAGGCATACTGTGATTAGCAATGCATGTTTATGTAG
Downstream sequence
TGAGACACCAGATTAGAAATGATTATTATCATGTCACCTAACAGAGTGATAATAATGGTACTCTGAGATGGTACAGCTCAGCTGTTGAGGATTCCTACTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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