Basic Information
VIS ID
TVIS30008489
Fusion event
HIV-ECT2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
172537550/172819760 (Hg38)
End
172537550/172819760 (Hg38)
Orient
-
Location type
Intronic
Target gene
ECT2
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-132-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-96-5p ; hsa-mir-27a-3p ; hsa-mir-26b-5p ; hsa-mir-30c-5p ; hsa-mir-223-3p ; hsa-mir-3591-5p ; hsa-mir-141-5p ; hsa-mir-4255 ; hsa-mir-142-3p
Nearest miRNA
hsa-let-7g/Upstream/1713001; hsa-mir-1224/Downstream/2549780;
Nearest TSS
ENST00000440867/Upstream/1429; ENST00000447709/Downstream/321508;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/68705, chr3-CpG: 49/Downstream/575720
Nearest cancer related gene
ECT2(OG, No orient, 0)
Upstream sequence
CTCACATATGTACATCTGAGTTGTACATATATTACAAACACTCTTTGAGAGTGTATGACTTAATTTTAGAAAATTATTTCCCATGAAGTGATTTCATTCC
Downstream sequence
TTTTAATTCTGCTTTATGAACTAAGAAGAAACCTTGTTTGCCAATTTATAATTTTTTCTTTTATAACCTGAAACACTGAATCATTAATATTTCATAAAAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate