Basic Information
VIS ID
TVIS30008495
Fusion event
HIV-PIK3CA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.32
Reference genome
GRCh37/hg19
Start
178952727/179234939 (Hg38)
End
178952727/179234939 (Hg38)
Orient
+
Location type
Intronic
Target gene
PIK3CA
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-148b-3p ; hsa-mir-335-5p ; hsa-mir-17-5p ; hsa-mir-375 ; hsa-mir-1-3p ; hsa-mir-155-5p ; hsa-mir-490-5p ; hsa-mir-203a-3p ; hsa-mir-139-5p ; hsa-mir-373-3p ; hsa-mir-422a ; hsa-mir-19a-3p ; hsa-mir-10b-5p
Nearest miRNA
hsa-let-7g/Upstream/2719788; hsa-mir-1224/Downstream/4651861;
Nearest TSS
ENST00000440867/Upstream/15388; ENST00000483460/Downstream/8345;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/85819, chr3-CpG: 62/Downstream/26221
Nearby gene
PIK3CA(No orient, 230)
Nearest cancer related gene
PIK3CA(OG, No orient, 0)
Upstream sequence
ATTTCTTATTTTTCCATTGCTGTTCAATTTATAGTTTGAAGTGGGTTTTTGACTGCTTGTTTAATGAAGAAAAATGCTTGGGGTGGAAGGGACTCTTGAG
Downstream sequence
ATTTCACCAGAGACTTTTTCTTTTTAATAAATCAAACCTTTTGATGATTTGAGGTTTTATCTGCAGTTTTGGAAGCAGTCACAAATGAGACCTGTTATAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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